Some people hate Tylenol. Although dentists and surgeons love the drug – especially when laced with ibuprofen – studies show acetaminophen, the generic form of Tylenol, can be a liver toxin. But a sound body of data linking the drug with neurological deficits is wanting. Nevertheless, people are blaming this “modern-day menace” for autism and ADHD – and hundreds of cases claim exposure in utero caused the conditions. What does the court say?
acetaminophen
Since 2020, we have been able to buy Advil Dual Action, OTC pills that contain a fixed dose of acetaminophen (Tylenol) and ibuprofen (Advil). Who benefits from combining two medicines into one pill? Is it patients – or GSK that makes the product? I maintain it's the latter.
Advil, aka, ibuprofen, is one of the most widely used drugs in the world. It's effective for relief of pain, inflammation, and fever. It can also wreak holy hell on your stomach. Unfortunately, the two effects go together. Grab the Rolaids. It's time for an Advil lesson.
If it were April 1st, you'd probably treat the concept of "Vegan Tylenol" as a practical joke. But it's September, and a company is actually selling the stuff.
The deluge of the use of the term "natural" for product promotion continues unabated. But perhaps it's getting stale because KinderFarms, Jessica Biel's company, is selling stuff like Tylenol and Benadryl with the promise of avoiding "artificial petrochemicals." That ignores the fact that these drugs are all made from just that. Nope, no kindness or farms. Just another misleading ad campaign.
In 2017 I did an extensive search of Cochrane Reviews that addressed the efficacy (lack, really) of Tylenol (acetaminophen) in controlling pain. With few exceptions, it did little or nothing. In the six ensuing years, there have been more published on the efficacy of the drug. And the message is the same.
Johnson & Johnson is working on a drug to repair liver damage caused by Tylenol, which has made the company billions since it was launched in 1955. Isn't this a bit like having a dentist's office in the back of a candy store?
When government, politicians, and law enforcement take control of the practice of medicine this is what we get: Cruelty and incompetence. The next time you're given Tylenol for a broken leg or post-surgical pain you'll understand. Drs. Jeffrey Singer and Josh Bloom in USA Today.
Trip report: Josh goes into a Manhattan CVS to buy some Tylenol and is horrified by generic drug discrimination. Then he steals a piano.
IV Tylenol is commonly used to control pain following surgery. But, should it be? A randomized, double-blind, placebo-controlled trial – the gold standard – of patients who underwent abdominal surgery gave us a very clear answer. Take a wild guess.
Summary: In the mad dash to remove opioids from modern life, some researchers are willing to try anything, even Tylenol to control pain. How well does IV Tylenol work for post-operative pain from spinal surgery? Although the data are not complete, it's safe to say that it's no better than moose urine.
A new study in the British Journal of Clinical Pharmacology suggests increased use and overdosing of the pain reliever and fever-reducing medication during this period. But what explains it?