Nicotine is an addictive substance; it is THE addictive substance in tobacco, although tobacco’s combustion products are responsible for most of its adverse health effects. Nicotine has been in the news a lot between the plan to remove JUUL, a nicotine delivery system from the market, and the FDA proposal to require cigarettes to have lower nicotine levels. I asked myself a simple question for which I did not have a ready answer, what amount of nicotine is necessary to get you addicted – what dose makes the poison?
