VX-458

There's a vital need for new and effective pain medications. Vertex just announced results from a Phase III study of its experimental drug VX-548. How well does the drug work? It's hard to tell. Here's why.
There's considerable ongoing research to develop analgesic medications that don't have the liabilities of NSAIDs and opioids. Many potential drugs are in various stages of development. Most will fail. This multi-part series will examine drugs in development and their potential utility. First up is VX-458, a Phase III candidate from Vertex.