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NICOTINE & HEALTHEvery day, it seems, another scare story appears warning everyone smokers, non-smokers, parents, teens, vapers (e-cigarette users) about alleged, hypothetical, minuscule, inane, and/or politically-motivated threats arising from e-cigarettes or one of their components. These potentially toxic, addictive, or merely seductive substances include propylene glycol, glycerine, water and its vapor, nicotine, and the heating element.

But none of these alarmist jeremiads bother to mention the 44 million American cigarette smokers...

We have had a recent and unfortunate encounter with a website called DeSmogBlog, whose stated aim is "clearing the PR pollution that clouds climate science." In reality, it's an ideologically driven, propaganda website that spreads malicious disinformation and smears scientists like the late Dr. Freeman Dyson.

And irony of ironies! While claiming to be on the side of science, DeSmogBlog Executive Director Brendan DeMelle is an anti-vaxxer.

His bio page proudly notes that he "served as research associate for Robert F. Kennedy, Jr." As we have written before,...

Pregnant SmokerAccording to new data from the Centers for Disease Control, over 8 percent of pregnant women in America smoke. That's about one-half the overall smoking rate among adults but given the dire consequences for the fetus and baby, it's still way too high.

The habit is most prevalent during the first...

“Banning menthol—the last allowable flavor—in cigarettes and banning all flavors in cigars will help save lives, particularly among those disproportionately affected by these deadly products. With these actions, the FDA will help significantly reduce youth initiation, increase the chances of smoking cessation among current smokers, and address health disparities …Together, these actions represent powerful, science-based approaches that will have an extraordinary public health impact.” FDA Statement by Acting FDA Commissioner 

Janet Woodcock, MD

...

The pharmacokinetics of ethanol and THC differ quite a bit. From a metabolic point of view, despite how some feel the “morning after,” ethanol has a short half-life of 1 to 2 hours. THC, whether smoked or swallowed, hangs around far longer, one to two days. While both ethanol and THC undergo metabolism in the liver, ethanol is primarily metabolized by alcohol dehydrogenase, forming water and CO2. By contrast, THC undergoes hepatic metabolism to form various metabolites, including the psychoactive 11-hydroxy-THC. Furthermore, THC, being a lipophilic (fat-loving) chemical, is stored in body fat, where it is slowly released.

Two problems arise:

  • We can equate a given blood level of alcohol with impairment, but that is not the case for THC because of its...

Working for the “opposition” is neither new nor restricted to regulators. Many criminal defense attorneys learned their trade as prosecuting attorneys. And in Washington, sometimes it is more of a revolving, rather than a one-way door, with a regulator coming and going from public service and the private sector with changing administrations.

Matt Holman was the director of the Office of Science at the FDA’s Center for Tobacco Products; Keagan Lenihan was an associate commissioner for external affairs and strategic initiatives and is now VP of governmental affairs and public policy at Philip Morris. This is the second departure from the FDA to Philip Morris in the last few weeks.

What do these regulatory captures bring to the table?

In general,...

The novel coronavirus, officially dubbed SARS-CoV-2, and the disease it causes (COVID-19) have continued to surprise all of us. And the surprises have been uniformly negative.

When the pandemic first began, it was obvious that the coronavirus would pose, at the very least, a substantial regional threat. That's why we scolded the World Health Organization for dragging its feet in declaring a global public health crisis. We pondered, probably correctly, that WHO Director-General Dr. Tedros was trying to keep China happy. For this and other reasons,...

Many of us will recognize Daniel Gilbert as a retirement fund spokesman, helping us see just how long our retirement funds will last with dominos, ribbons and sticky notes. But his real job is being a psychology professor, and he has recently co-authored a short but impactful paper in Science on another bias in our judgments. When we describe aspects of the world, big or small, few or many, we compare what we see with some relevant reference value. When we think about how often something occurs, our remembrance of its prior frequency influences our judgment – psychologists term this prevalence-induced concept change. The study reports on seven simple experiments.

The Study

In the first study, people were shown dots of color ranging from very purple to...

With the current wave of states legalizing marijuana, advocates championing the cause and the presence of greater societal acceptance, there is a growing perception that dispensary-supplied “medical marijuana”—not distinct from “recreational marijuana”— is as safe as any medical product obtained at a pharmacy. This is not so as there are no quality control measures or thorough federally-regulated vetting procedures in place to ensure safety.

It seems the medical and health research aspects of the issue are many steps behind the legal and political advances contributing to a false sense of security. The reality is much is not known about the science—good, bad or indifferent. Partly to blame is public universities’ very restricted ability to study the substance in the first place...

A new paper seeks to inform concerns about e-cigarettes, purportedly used as harm reduction and smoking cessation techniques, being a gateway to smoking.

The conclusion by Hongying Dai and Jianqiang Hao is that e-cigarettes, and especially flavors, do lead to both cigarette smoking and an unwillingness to quit. There is just one problem - there is no data showing that. (1)

Pediatrics is a good journal to be addressing this issue. The American Council on Science and Health has long shown that smoking is a pediatric disease. Like many other habits, if we prevent them in youth, we can prevent them throughout life. But we also...