Alzheimer's disease

Biogen's latest effort at an Alzheimer's Disease treatment has been withdrawn. Treating biomarkers, measurable substances associated with a disease -- in this case, plaques -- will not work.
Science and medicine often move in small, incremental steps. A framework for researchers studying Alzheimer's Disease won't make the evening news, but it is a victory in a much longer battle. We should pause to acknowledge the quiet work of our scientists and clinicians. 
One type of malady that most people really hope to avoid is Alzheimer's Disease. As the population ages, this disorder and similar ills will likely become more common. While much research has been devoted to figuring out how to forestall these problems, recent studies indicate we still have a long way to go to get there.    
Death rates for Alzheimer's Disease have risen 55% between 1999 and 2014. That's according to the Centers for Disease Control and Prevention’s latest Morbidity and Mortality Weekly Report. Here are the reasons why this is occurring, and the trend's implications.
The key to preventing Alzheimer's Disease may lie in the North Atlantic island of Iceland. Its relatively homogeneous population has been a treasure trove for genetic researchers looking for mutated genes that either increase or decrease the disease's risk.
Our views on egg consumption — at least as far as heart disease goes — have changed dramatically in the past decade. They're no longer seen as a dietary villain. A new study suggests that not only do eggs not contribute dementia, which had been suggested by some animal studies, they may also be linked to a lower risk of such ailments.
Now that winter has hit the northern hemisphere, our thoughts often focus on ways to keep warm. Well, not only can a nice, sweaty sauna do the trick, but according to a recent study repeated saunas may just help fend off dementia — at least for middle-aged men.
The prevalence of dementia in the United States significantly declined from 11.6 percent in 2000 to 8.8 percent in 2012. The consequence of this impacts retirement, families, the health care system, life expectancy, morbidity and mortality, pensions, housing, transportation and countless societal realms. 
A new CDC report reveals surprising and disturbing findings regarding overall death rates in America. They were found to have risen last year, albeit slightly, as compared to the year before. The cause, or causes, of this upturn are unknown, but should be pursued.
A new study shows a strong association between androgen-deprivation therapy for advanced prostate cancer, and the development of Alzheimer's disease. This is a retrospective data-based study, so no change in treatment using ADT is indicated now. Further, prospective studies are needed.
A new study using PET scans on the brains of older individuals shows a three-fold higher risk of mild cognitive impairment (MCI) among those with elevated levels of amyloid-beta, a proteinaceous material associated with neurodegeneration. MCI is a known risk factor for Alzheimer's disease.
Simple lifestyle interventions are a tempting target to stave off cognitive decline and Alzheimer's disease. Sadly, two new studies appearing in JAMA show no discernible benefit from exercise activity nor from omega-3 or vitamin supplementation.