The U.S. Supreme Court ruled that "the liberty secured by the Constitution of the United States to every person within its jurisdiction does not import an absolute right in each person to be, at all times and in all circumstances, wholly freed from restraint. There are manifold restraints to which every person is necessarily subject for the common good." Mask and vaccine mandates, therefore, are, under some circumstances, constitutional.
In February, 2021, the CDC published its mask mandate in the federal register requiring a person to “wear a mask while boarding, disembarking or traveling on any conveyance into or within the United States.” Exemptions were provided for specific medical conditions. Several plaintiffs suffering anxiety disturbances from masking (which was not exempted) sued the CDC in Florida district court for exceeding its statutory authority (and for other issues). The court ruled in favor of the plaintiffs and is on appeal. The case directly addresses the powers of the CDC to act during public health emergencies in interstate transport and commerce.