The U.S. Government doesn't want to hear the message: The Centers for Disease Control and the Veterans Administration published practice guidelines on the prescription of opioid pain relievers in 2022 that they knew were unsupported by science and harmful to public health. The Department of Health and Human Services is stone-walling repeated demands for a senior staff review of these issues.
For reasons I cannot fathom, we are treated to yet another clinical trial about IV Tylenol and whether it can decrease the amount of morphine needed by pain patients in the ER. Here's your hint: No.
Antibe Therapeutics has been developing otenaproxesul, a "miracle drug" that, at least in early trials, controlled both pain and inflammation -- but without the side effects of NSAID drugs. However, the company hit a snag and is now going in a different direction. Will it succeed?
Bad headlines are ... bad. Sometimes they're bad enough that they screw up the story to the point where the headline says one thing and the paper, study or story says another. The folks at the Hospital For Special Surgery in New York did just that, by issuing a press release which suggested that Tylenol is useful for pain following hip replacement. But the study says no such thing. In fact, another study says it's useless.
A new study published in JAMA indicates that people who make emergency room visits for pain do just as well with Advil as they do with an opiate. Or do they? The pain devil is in the details.
An article recently published in the British Journal of Pharmacology discusses the synthesis of a molecule, PnPP-19 and its ability to block pain perception and potentiate erections. So as it turns out, not all spider venom is bad – in fact, it can be pretty great.