There is a naturally-occurring chemical called skatole. Its claim to fame is that it is named after, and smells like, fecal matter. It's "synthetic" but also "man-made" and there's a revolting distinction in this case. It's also an additive used in cigarettes and strawberry ice cream (??). Do your "duty" and read this article.
The Environmental Working Group has once again released their Dirty Dozen list — the fruits and veggies they say are covered in pesticides. One minor detail: organic produce contains pesticides, too, but that doesn't quite fit their narrative.