Congestive heart failure refers to the inability of the heart to perform its basic function, which is pumping blood throughout the body. It comes in various forms, causing swelling of the legs and shortness of breath. It is a very debilitating condition that few outside medicine are aware of. A new study offers a unique treatment, but more importantly for our discussion, it sheds light on how “science” advances and looks at an infrequently used term, hormesis.
World War II ended with the bombings of Hiroshima and Nagasaki. Those bombings and the late effects of radiation on the development of cancers in those “survivors” spurred scientific inquiry into the mechanisms underlying human carcinogenesis – the development of cancer. Today’s regulatory science of chemical carcinogens is based upon assumptions and beliefs that are now 75 years old. Our understanding of carcinogenesis has evolved; should our regulatory models shift?
The EPA’s model for assessing the rise of carcinogenesis from chemicals and their dose-response models remains controversial. Is the EPA “following the science” or making assumptions?