organic synthesis

Remdesivir, the most promising anti-coronavirus drug at this time is no fun to synthesize. But Gilead, the drug's maker, is synthesizing a whole bunch of it. Does this tell us anything about whether the drug works? Maybe.
Two of the experimental coronavirus drugs, chloroquine, and hydroxychloroquine are a breeze to synthesize. But remdesivir, possibly the most promising candidate, is anything but. It's a royal pain. Here's why.
Two Arkansas professors were recently charged with making methamphetamine. But the chemical that police found was a simple reagent called benzyl chloride. Are these guys guilty? It all depends on the chemistry.
Some chemicals are so dangerous that even experienced chemists hate to use them. Here's a real doozy. Diazomethane is an explosive, highly toxic gas, which is a carcinogen. It is made from another toxic carcinogen and the chemical that makes Drano work. Aside from that, it's just fine.
A Chinese group just pulled off something that has eluded chemists for decades. Chemists made and isolated a simple, but highly-unstable creation called pentazole for the purpose of studying it as an explosive. And they didn't even blow themselves up.