Does caffeine intake weaken antibiotics in your system?

By Ana-Marija Dolaskie — Sep 08, 2025
Could drinking caffeine potentially weaken antibiotics in your system? A recent study says maybe. Sounds alarming, right? But don't ditch your latte just yet—let’s dig into the facts.

Scientists in Germany tested 94 substances on E. coli in a lab. They found that caffeine flips a switch in the bacteria called Rob, which makes it harder for certain antibiotics. This could make antibiotics less effective. 

Scary, but here’s the catch: this was a petri dish experiment, not a human trial. Lab conditions don’t mimic the complex environment of the human body, where digestion, metabolism, and immune responses change how substances interact.

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