A new study using PET scans on the brains of older individuals shows a three-fold higher risk of mild cognitive impairment (MCI) among those with elevated levels of amyloid-beta, a proteinaceous material associated with neurodegeneration. MCI is a known risk factor for Alzheimer's disease.
Two large meta-analyses in JAMA shed light on the link between Alzheimer s disease and amyloid beta (A-β). The key findings indicate that it is likely to take up to 30 years of amyloid deposition before clear signs of dementia are manifest but such deposits are not diagnostic.