Prohibition of drugs simply doesn't work. Clamping down on Percocet and Vicodin resulted in a surge in heroin use. Fentanyl took care of that market and now even worse drugs called nitazenes are being found in fentanyl samples. Dr. Jeff Singer and I discuss this latest development in USA Today
We sure need a new pain medicine without the baggage of NSAIDs or the stigma of opioids. Johnson & Johnson thinks it might have an answer - a derivative of Tylenol without the associated liver toxicity. But does it treat pain? Not very well.
I've been following (and writing about) Antibe Therapeutics' otenaproxesul, an atypical NSAID without the GI toxicity of Aleve or Advil, since early 2020. It's been nothing but good news. Until now. Otenaproxesul caused a substantial jump in liver enzymes in some clinical trial participants. Can the company overcome this? Wall Street sure doesn't think so.
Dr. Josh Bloom in the New York Post, December 2, 2013 Thanks to a thoroughly misguided move by federal drug bureaucrats, many Americans are going to have to live with needless pain...[Read more.]