A small, but well-conducted, study of the effect of CBD oil on bad toothaches neither proves nor disproves whether the drug works. However, some intriguing data could be confirmed in a larger clinical trial. Let's call this mildly encouraging. At best.
randomized controlled trials
The controversy surrounding ivermectin as a therapy for COVID has been longstanding and fierce. A recent paper in NEJM may or may not settle the ongoing debate. But the paper is full of data. Here is a condensed look at the key numbers.
Certain kinds of scientific literature reviews can bias experts into being more optimistic about the potential outcome of a clinical trial than the data actually warrant.
Another clinical trial of remdesivir – this time with hospitalized patients having moderate COVID-19 – yielded disappointing and strange results. The first randomized trial showed a modest benefit in patients with severe COVID, so theoretically the drug should have worked better in patients who weren't as sick. But, it didn't.
The foundation of medical research, which is considered the gold standard, is the Randomized Controlled Trial when individuals are matched with others, and then randomized to one treatment or another. While the beauty of an RCT lies in its process of deliberate randomness, very little attention has been paid to the integrity of its building blocks: categories. It's time to take a more in-depth look.
It's only one trial, and we don't even know if the report is correct. But a leaked draft report indicated that remdesivir was ineffective in its first controlled trial. Let's assume that this is true and we see the same from other trials. If so, this will not simply be another experimental drug failing. It will be deeply disturbing. Here's why.
Preliminary data, obtained from a randomized clinical trial of remdesivir in China, look bad. Maybe even very bad. But this doesn't mean that the drug won't be shown to be useful in other trials. Nonetheless, not good news.
How many times in the last week have you seen headlines such as Coffee as a memory booster, or How Diet Soda Makes You Fat? Well, according to a study conducted by researchers in