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Quick quiz: What is the world's most deadly human pathogen for which there is no vaccine? Since the title, unfortunately, must precede the article, you already know the answer. Norovirus, which is incorrectly called the "stomach flu," isn't a virus that most people would associate with death (although you may prefer to be dead if you catch it), but its annual death toll is estimated to be 200,000, mostly due to dehydration in developing areas that lack clean water.

But a group at the Washington University School of Medicine in St. Louis may have discovered what makes the bug so nasty which may also represent a possible way to exploit this nastiness to help discover a badly-needed drug or vaccine.

To add to its splendid array of qualities, norovirus, which got its name...