Illicit fentanyl continues to kill tens of thousands of people annually in the U.S. In fact, this number may very well be increasing as the "fentanyl epidemic" continues unabated. But now a fentanyl vaccine – which could be of some use in mitigating damage – appears to protect mice from the drug. Will it succeed in humans and, if so, how might it be used?
It's intuitive that a robust immune response to COVID-19 will result in a less severe, even asymptomatic infection. A new study puts some numbers to the term "robust."
As was the case with other "instant therapies" for COVID, convalescent plasma showed no utility whatsoever in a well-designed randomized controlled trial, something that should come as no surprise to anyone who has ever waded in the treacherous waters of drug discovery research. Another one bites the dust.
COVID may trigger autoimmune disease in some people, contributing to their deaths.
People with lower levels of antibodies against mumps -- the second "M" in the MMR vaccine -- are likelier to have a severe case of COVID.
“You can think of the human immune system as an orchestra playing together and needing a co-ordinated performance from all the musicians and their instruments. It doesn’t make scientific sense to talk about antibodies or T-cells on their own.”
We have made amazing progress in the treatment of COVID-19. Two therapies – steroids and remdesivir – have already been shown to help. Those who benefit from these treatments owe thanks to patients who volunteered to participate in controlled clinical trials, and the physicians and pharmaceutical companies that lead them.
Yes, it's a good idea to go to the doctor every once in a while -- annually, of course, is best. As he or she is prodding about, your doctor might find something rather unexpected. In my case, he found that I'm no longer immune to this disease.
Some migraine sufferers are easily treated with triptans or opioids. Other migraine sufferers, however, aren't so lucky. Perhaps immunotherapy will provide relief. Several companies are working on injections of anti-migraine antibodies.
Scientists from two universities and the National Institutes of Health are developing a vaccine to defeat norovirus' defense mechanism: mutation. By targeting a "conserved region" -- the part of the viral capsid that does not mutate -- they have discovered an antibody that may cover most strains that circulate now, as well as those that might circulate in the future.
Does your blood type – specifically, your Rh factor (positive or negative) – matter in your daily life? Not in the slightest. But when pregnant your Rh status can matter, especially if it's negative.
Those with severe eczema can suffer mightily from itching, which leads to scratching, which makes it worse. Anti-inflammatory steroids are the go-to drugs (but they have many nasty, long-term side effects). But an antibody drug named Dupixent, just approved by the FDA, works very well. So now you may be able to give your fingernails a rest.