The FDA is conducting a workshop to discuss the science (lack thereof, really) of Morphine Milligram Equivalents as it applies to the atrocious CDC 2016 Opioid Prescribing Guidelines. Public comments have been solicited. Here are mine.
Can you use a Dreaded Chemistry Lesson from Hell (TM) to take your mind off your woes? If so, dive right in.
GHB, one of the "date-rape drugs," is being increasingly abused after two decades of low usage. Here's a lesson on the chemistry, biochemistry, and nomenclature of the drug. Admittedly, this sounds deadly boring. But there's more. Juvenile puke humor! Enjoy.
Despite irrefutable pharmacological evidence of the wide range in individuals' metabolism of opioid drugs, states continue to impose "one-size-fits-none" laws. For example, Massachusetts, apparently not entirely at peace with the abolition of the Salem witch trials, became the first state to establish a seven-day limit on first-time opioid prescriptions. Others followed. It's safe to say that no one is really paying attention to the science. So, here it is. Again.
Heroin is like a box of chocolates. And it wasn't invented in Germany. And it's (technically) harmless. To make sense of all this gibberish you better read the article. A bunch of stuff you might not know about H.
Should you be in the mood to change the color of your pee, this is the article for you. Two drugs and one natural product do the job quite vividly. A colorful chemistry lesson, a party trick, and good bathroom reading!
The cell is amazingly energy efficient. Capable of trapping about 38% of the energy that it receives from sugar, it may be the most energy efficient machine on Earth.
Sometimes taking a second drug can have a profound effect on one that's already being taken. That's because it can cause abnormally high or low blood levels of the first drug. This is known as a drug-drug interaction. Opioids are used as an example of how this works.
Depression and anxiety are not always easy to detect. Symptoms can range from worry to chronic indecision. Thus, an easily detectable biomarker for would be preferable, and Chinese scientists believe they have found one using a urine test.
Synthetic cannabinoids are sometimes mixed with rat poison, which causes uncontrollable bleeding. So, as it turns out, the neighborhood drug dealer might not be a completely trustworthy individual.