The FDA has at this time received 79 comments for its "Morphine Milligram Equivalents: Current Applications and Knowledge Gaps, Research Opportunities, and Future Directions; Public Workshop." Here is the 80th.
The FDA is conducting a workshop to discuss the science (lack thereof, really) of Morphine Milligram Equivalents as it applies to the atrocious CDC 2016 Opioid Prescribing Guidelines. Public comments have been solicited. Here are mine.
If you don't learn anything from this pharmacology lesson, at least remember this one thing: Call your doctor if your erection lasts longer than 4 hours. Seriously.
For every additional microgram per liter of lithium in the water supply, the suicide rate dropped by 0.27 per 100,000 people per year.
Despite irrefutable pharmacological evidence of the wide range in individuals' metabolism of opioid drugs, states continue to impose "one-size-fits-none" laws. For example, Massachusetts, apparently not entirely at peace with the abolition of the Salem witch trials, became the first state to establish a seven-day limit on first-time opioid prescriptions. Others followed. It's safe to say that no one is really paying attention to the science. So, here it is. Again.
Andrew Kolodny's lack of knowledge of pharmacology is legendary. His chemistry must be far worse. Should I be flattered when he appears to be copying mine? "Imitation is the best form of flattery." Charles Caleb Colton, 1824 ... "Except when it makes me want to puke." Josh Bloom, 2019
The self-proclaimed expert on opioids and addiction "agreed" to sit down with me and answer some tough questions about his background, medical insight and plans for the future. (Keep in mind that this "interview" took place on April 1.)
A group of academics, bureaucrats and self-appointed addiction experts put their collective heads together and their collective noses where they didn't belong. They produced the 2016 Guideline for Prescribing Opioids for Chronic Pain, an abysmal failure. Here are what's wrong with it and some ways to undo the damage.
There are calls to incentivize antibiotics research. While it is welcome that government again understands the importance of pharmaceutical discovery, it's not that simple.