Drugs & Pharmaceuticals

Safety data based on more than 17 million Pfizer and Moderna COVID vaccinations was just published in a JAMA online article. How safe were they? Very.
Given recent events, including Europe's botched approach to procuring a COVID vaccine, do we think the E.U. will be able to get it together to provide a significant pull incentive for antibiotic research and development?
Canadian pain patients may have it even worse than those in the US. Our northern neighbors are buying opioids on the dark web (shudders) because they can't get them from their doctors, just like here. Perhaps we need a "Borders Without Doctors" group.
At some point, we're gonna run out of people to deny opioids. What to do?? There are many anti-opioid zealot mouths to feed. New victims are needed. How about cats?
Among the unpleasant effects of COVID is a whopping portion of aches and pains. Whether there is anything you can take to feel better -- for example, Advil -- is not clear. But two, large retrospective studies seem to give the thumbs-up to NSAIDs.
If you don't learn anything from this pharmacology lesson, at least remember this one thing: Call your doctor if your erection lasts longer than 4 hours. Seriously.
IV Tylenol is commonly used to control pain following surgery. But, should it be? A randomized, double-blind, placebo-controlled trial – the gold standard – of patients who underwent abdominal surgery gave us a very clear answer. Take a wild guess.
It would have been impossible to predict the efficiency of the COVID vaccination program at the newly-opened Fort Washington Armory location. It was amazing. Including the seat wiper.
Seven human health risk assessments of pharmaceuticals in drinking water in the U.S. and Canada were reviewed. And good news: None of these studies reported a potential health risk from exposure to pharmaceuticals in drinking water.
It has long been known that different people react differently to opioid drugs, and by a wide margin. This means that the same dose may be too high for one person and too low for another. The difference can be due to genetic differences in metabolism. Can science be used to determine not only the dose but also the best opioid for an individual?
It's no secret that NSAIDs come with a host of side effects. But how often? And how bad are they? A presentation at the 2020 PAINWeek Conference gives us some numbers. If taken at face value they are horrifying.
The COVID vaccine is out -- and no one needs it more than the elderly. But vaccines don't work as well in older people. A group at Oxford is trying to address this by adding a simple (but nasty-smelling) naturally-occurring chemical that makes damaged cells eat themselves.