Yet another potential Covid treatment has fallen by the wayside. This time it's fluvoxamine, an antidepressant, which showed some promise in minimizing serious disease in small trials. But in a large, randomized trial, it flopped completely. The lesson? You need an antiviral drug to treat a viral infection – not a repurposed drug. These have all failed.
Let’s continue our countdown of the top articles written by ACSH this year.
Paxlovid, the most effective Covid drug to date has its share of critics. But is the criticism fair? Drs. Henry Miller (an ACSH advisor) and Josh Bloom examine the benefits and limitations of the drug.
News organizations have recently been down on Paxlovid, while it has become the standard of care. Some claim Pfizer's Covid drug "has lost its luster" because of "failures" in two clinical trials. Now, a third trial looks like it could deliver another black mark: the drug doesn't improve symptoms in low-risk patients with Covid. Is this criticism valid? Let's look a little deeper.
There's been a lot of news, some of it fear-mongering, about Pfizer's Covid drug Paxlovid. Some people are having their symptoms return after completing the five-day course. Does that mean there is something wrong with the drug, or it's simply a property of the virus? Drs. Henry Miller and Josh Bloom try to provide an answer in Issues & Insights.
A Boston Globe article describes COVID-19 patients completing a course of Paxlovid – and then becoming ill again shortly thereafter. Is there something wrong with the drug? Is this something to worry about?
Two months ago, there was a mad rush to get the two oral antiviral pills approved to treat COVID-19. Pharmacies often ran out of these drugs within hours of delivery. Now, no one wants them. What is going on?
Should the COVID drug Paxlovid be available without a prescription? Some argue that pharmacists should be able to distribute the drug to people who have tested positive for COVID while others, including the AMA, believe that only physicians should be able to prescribe the drug because of some potentially dangerous drug-drug interactions. Cato Institute's Dr. Jeffrey Singer weighs in.
The Biden administration announced a "test to treat" plan to provide easy access to Paxlovid – an effective COVID antiviral drug – for anyone who's infected. It's not perfect, but it's sorely needed.
It's been an interesting month COVID-wise. The COVID antivirals made their way to pharmacies. All in all, things went pretty well (unless you happen to be Merck). Here, you'll learn how to locate pharmacies in your area that have been selected to carry the drugs, and how to see if the pills are in stock.
Patients and their doctors have voted with their scripts. Overwhelmingly, they are choosing Pfizer's Paxlovid and rejecting Merck's molnupiravir. So much so that when Paxlovid is unavailable (which is most of the time) many don't even bother to try the other option. Surprising?
Two newly-approved antiviral drugs against COVID are now available to those who need them. But the FDA is getting in the way with unwise and counterproductive requirements. Drs. Jeffrey Singer and Josh Bloom explain in their Op Ed in the New York Daily News.