If it were April 1st, you'd probably treat the concept of "Vegan Tylenol" as a practical joke. But it's September, and a company is actually selling the stuff.
Tylenol
Evidence suggests that Tylenol isn't an effective pain reliever in many cases, so why do doctors rely on it post-surgery? When it comes to treating and discussing COVID-19, do doctors have the right to speak freely, even when they dissent from accepted medical wisdom?
In 2017 I did an extensive search of Cochrane Reviews that addressed the efficacy (lack, really) of Tylenol (acetaminophen) in controlling pain. With few exceptions, it did little or nothing. In the six ensuing years, there have been more published on the efficacy of the drug. And the message is the same.
Cutting the dose of Tylenol in opioids makes the drugs safer. Why? Pharma company Johnson & Johnson is developing a drug that could reduce liver damage caused by Tylenol — which J&J also sells.
Johnson & Johnson is working on a drug to repair liver damage caused by Tylenol, which has made the company billions since it was launched in 1955. Isn't this a bit like having a dentist's office in the back of a candy store?
Will Tylenol alleviate severe pain? It will not, yet patients are routinely given the drug after major surgery. Thank your congressman for such insanity. Meanwhile, the drug store conglomerate CVS displays real pain relievers right next to useless homeopathic "remedies." A lawsuit could put an end to that dubious marketing practice.
There are plenty of reasons for skepticism about medical studies. Some are poorly designed or performed, and some conclusions are totally implausible. In addition, some interpretations of them are intentionally misleading, and some studies need not have been done at all.
When government, politicians, and law enforcement take control of the practice of medicine this is what we get: Cruelty and incompetence. The next time you're given Tylenol for a broken leg or post-surgical pain you'll understand. Drs. Jeffrey Singer and Josh Bloom in USA Today.
We sure need a new pain medicine without the baggage of NSAIDs or the stigma of opioids. Johnson & Johnson thinks it might have an answer - a derivative of Tylenol without the associated liver toxicity. But does it treat pain? Not very well.
Trip report: Josh goes into a Manhattan CVS to buy some Tylenol and is horrified by generic drug discrimination. Then he steals a piano.
Among the unpleasant effects of COVID is a whopping portion of aches and pains. Whether there is anything you can take to feel better -- for example, Advil -- is not clear. But two, large retrospective studies seem to give the thumbs-up to NSAIDs.
IV Tylenol is commonly used to control pain following surgery. But, should it be? A randomized, double-blind, placebo-controlled trial – the gold standard – of patients who underwent abdominal surgery gave us a very clear answer. Take a wild guess.