Drugs & Pharmaceuticals

Is sticking your finger down your throat a pleasant experience? (Sorry, bulimics excluded) How about sticking it down there and leaving it for three weeks? This is not a gag (sorry).

One of the many horrors that drug discovery chemists constantly wrestle with is called pharmacokinetics (PK) – the science of what the body does to a drug (1).

Does it make any sense to use an antibiotic like this?

Pricing a new drug is not an easy task, Gilead who is producing remdesivir is no stranger to pricing controversy, the release of Solvaldi, their drug to cure Hepatitis C, had a list price of $84,000 for a full treatment course.

Those who cannot remember the past are condemned to repeat it. (George Santayana). Never let a good crisis go to waste. (Churchill? Emanuel?).

What a letdown.

Six weeks of endless speculation, guessing, second-guessing, ups, and downs about whether the world would have its first effective coronavirus drug has been exhausting. I see the damn molecule in my sleep.

First, we do not know whether remdesivir has failed. Not by a long shot. The leaked draft document of a trial in China may or may not be real.

The world got a taste, albeit, a premature taste, of some bad news this afternoon.

Gilead Science is the Tom Brady of the antiviral research world. No other company even comes close.