In 1938 the FDA was given regulatory authority over experimental drugs. But it wasn't until 1961 that it regulated clinical trials and their methods. In 1954, a foundation performed a methodologically controversial trial with 1.6 million children, ages 6 to 8. It was called the National Foundation for Infantile Paralysis's Salk Vaccine Trial. As we hurdle at "warp speed" to a COVID-19 vaccine, perhaps we can reflect on how much has changed, or not, in our search for safe, effective vaccines.
In 1938 the FDA was given regulatory authority over experimental drugs. But it wasn't until 1961 that it regulated clinical trials and their methods. In 1954, a foundation performed a methodologically controversial trial with 1.6 million children, ages 6 to 8. It was called the National Foundation for Infantile Paralysis's Salk Vaccine Trial. As we hurdle at "warp speed" to a COVID-19 vaccine, perhaps we can reflect on how much has changed, or not, in our search for safe, effective vaccines.