Harm Reduction

One of the judgments made by scientists is how to aggregate or segregate data – especially when it comes to changing a continuous variable like age – into separate bins (10 to 18, 19 to 34, etc.). Race/ethnicity as a category has come in for some well-deserved criticism. Leave aside the argument that it is a social construct, race/ethnicity contains too many confounding features. A study in Nature points to a new way to break the category into meaningful segments.
Earlier this month, the headline “New Study Finds PFAS 'Forever Chemicals' in Drinking Water from 45% of Faucets Across US” led many news reports. That's after 32 individual PFAS were tested and found in both private and public water supplies, presenting potential hazards to our nation’s health. What did the study really say?
While academics explore the bounty and pitfalls that Artificial Intelligence (AI) offers, and Big Tech continues to hype the possible over the actual, the feds seek to make regulations. Corporate healthcare, in all its forms, is fighting back. Should we be techno-optimists, Luddites, or somewhere in between?
The World Health Organization’s (WHO) International Agency for Research on Cancer (IARC) recently concluded that the popular artificial sweetener aspartame, widely used in foods and diet drinks, is “possibly carcinogenic to humans,” an alarming conclusion because aspartame is used in thousands of low-calorie products. However, another WHO organization, the Joint Expert Committee on Food Additives (JECFA), concluded that it is safe to consume aspartame. Can we make sense of the conflicting conclusions?
While some extol the psychological benefits of psychedelics and bemoan their unavailability, at least one FDA-approved agent with psychedelic properties, Ketamine, does exist. The problem is that it is being abused- and oversight is wanting.
The FDA’s assault on vaping has yielded devastating consequences. Not only have millions of adults been denied legal access to low-risk vaping products they rely on to stay smoke-free, federal regulations are rapidly destroying thousands of jobs and billions of dollars worth of income, depriving ordinary Americans of their livelihoods. 
I’m at an age where I see doctors frequently enough that I noticed that the masks are gone. Will a surge in influenza or COVID this fall and winter bring masks back for all, or has COVID given us something other than a one-size-fits-all approach?
Conflict between Japan and China is not new. As the release of contaminated water from Fukushima into the Pacific Ocean has now been approved by the UN's International Atomic Energy Agency, China has issued warnings that this approval is insufficient. ACSH covered the underlying science last year; here is a reprise.
There are many shorthand rules and heuristics used in medicine. One of the classics: “When you hear hoofbeats, you don’t think of zebras.” It is a way of saying that, given a specific clinical presentation, you first look for the most common causes. A new paper in JAMA is concerned about those hoofbeats.
The U.S. Supreme Court ruled that "the liberty secured by the Constitution of the United States to every person within its jurisdiction does not import an absolute right in each person to be, at all times and in all circumstances, wholly freed from restraint. There are manifold restraints to which every person is necessarily subject for the common good." Mask and vaccine mandates, therefore, are, under some circumstances, constitutional.
The recent fires in Canada that resulted in a few days of heavy smoke-related air pollution in the Northeast have momentarily grabbed our attention. The very vocal "enviro-fearful" are concerned with more fires to come; the quieter "enviro-fearless" shrug it off as bad forest management. Each side accuses the other of bias in their interpretation of these events. There's another predictor of the future that has no such prejudice, and they're signaling their alarm by getting out.
On February 23, 2023, the World Health Organization released the “Zero Draft” (WHO CA+)  of their post-COVID Pandemic Preparedness Proposal, which some have categorized as a treaty. A final document is promised for 2024. Various governments and political factions have already trashed the draft, claiming it encroaches on the sovereignty of member nations. So, is it merely advisory, or is it binding?