As if fentanyl isn't bad enough, a series of opioid receptor agonists called nitazines is making its way into the street drug supply. But is this because the chemicals used to make fentanyl are now more difficult to obtain? It's certainly possible, if not likely. Organic chemists are nothing if not versatile.

“Oregonians voted in November 2020 to stop incarcerating people for using drugs unapproved by the federal government and instead direct resources to harm reduction programs. The pandemic got in the way. Now, while this project is still in its infancy, a group of Oregonians wants to replace something that hasn’t had a chance to work with something that we KNOW hasn’t and won’t work.”

Last week, the FDA and CDC presented their recommendations for the newest round of COVID-19 vaccines. As with everything COVID, there are proponents and detractors, or, putting it another way, both knowledgeable experts and disinformation-spreading attention-seekers. The reality is that a group of experts made a judgment based on actual data.  We discuss the evidence here so you can make your own informed decision.

In the wake of Hurricane Katrina in 2005, a physician was charged with manslaughter for administering morphine and a sedative to patients who couldn't leave the hospital during the disaster. Was she alleviating their pain and anxiety or trying to kill them? Meanwhile, many news outlets are paid to slant their science coverage. How did that happen, and what do we do about it?

Much has been written about Diversity, Equity, and Inclusion (DEI). Many who are adamant about diversity, especially in regulatory science, are less enthused over equity. I’ve had a few thoughts about both.

As an inveterate number cruncher, I couldn’t resist playing with a set of state-level data on prison populations that came my way. It has often been noted that the U.S. has among the highest rates of incarceration in the world. However, most of us feel that we enjoy a basically fair, just, and healthy society even though we are far from leading the world regarding life expectancies.

You may want to procure an air sickness bag before you read this. What's worse: A cigarette company portraying smoking as sexy (and it's not the least bit subtle) or a 1970 ad proudly proclaiming, "You've come a long way, baby" (as if the women's rights movement somehow empowered women by giving them their own brand of cigarettes)?

Two bills – one in Idaho, the other in the U.S. Senate – defy science, logic, and civic responsibility. The first would criminalize the administration of life-saving mRNA vaccines, while the second would ban mask mandates.

An FDA panel voted unanimously to withdraw the decongestant phenylephrine (PE) because it shows no benefit, something Sudafed PE users probably learned years ago. But the real story is why phenylephrine was on pharmacy shelves at all. It's all about the DEA and stupid drug policies, a story we've heard many times before.

The Cochrane Library recently completed a review of “the comparative benefits, harms and tolerability of different smoking cessation pharmacotherapies and e-cigarettes, when used to help people stop smoking tobacco.” Spoiler alert: as we have shown, e-cigarettes are a significant aid in reducing dependency on smoking tobacco.