Dangers of Poor Peer Review: They Aren’t Just Medical

Peer review has long been considered the gold standard guarantor of good science and medicine. It is also a rubric upon which legal standards of scientific admissibility are based. When the process fails – which is becoming increasingly common – medical practitioners and scientists alike are led astray, as is the law.  But while the scientific establishment is becoming aware of the concerns, such awareness is glaringly absent in the law.  

Peer review has long been considered the gold standard guarantor of good science and medicine. It is also a rubric upon which legal standards of scientific admissibility are based. When the process fails – which is becoming increasingly common – medical practitioners and scientists alike are led astray, as is the law.  But while the scientific establishment is becoming aware of the concerns, such awareness is glaringly absent in the law.  

FDA’s ‘Accelerated Approval’ Pathway for Drugs is Important, But Imperfect

By Henry I. Miller, MS, MD — May 25, 2023
Accelerated approval is intended to get needed drugs to patients, but there are sometimes distortions and complications in the process that should be addressed.

Accelerated approval is intended to get needed drugs to patients, but there are sometimes distortions and complications in the process that should be addressed.

Will That Be Cash or Credit?

By Chuck Dinerstein, MD, MBA — May 24, 2023
Credit card purchases, unlike those made with cash, are traceable. Leaving the value of untraceability for criminal enterprise aside, do consumers choose one over the other based on traceability? A new study suggests we choose cash when we wish to “forget” a purchase.

Credit card purchases, unlike those made with cash, are traceable. Leaving the value of untraceability for criminal enterprise aside, do consumers choose one over the other based on traceability? A new study suggests we choose cash when we wish to “forget” a purchase.

Will Pfizer's New Weight Loss Pill Silence the Ozempic Commercials?

By Josh Bloom — May 23, 2023
If you're one of the 100% of viewers who want to put a brick through your TV when one of the ceaseless, nauseating Ozempic ads comes on there's hope on the horizon. Pfizer has a pill that seems to work as well as the O-O-O-Ozempic injections. Perhaps this will shut up those wretched ads. A look at Pfizer's clinical trial data.

If you're one of the 100% of viewers who want to put a brick through your TV when one of the ceaseless, nauseating Ozempic ads comes on there's hope on the horizon. Pfizer has a pill that seems to work as well as the O-O-O-Ozempic injections. Perhaps this will shut up those wretched ads. A look at Pfizer's clinical trial data.

Every Picture Tells a Story: Melatonin

By Chuck Dinerstein, MD, MBA — May 23, 2023
Melatonin is a neurohormone that the body uses to regulate sleep. It's sold as a dietary supplement without a prescription. As the CDC states, in "2020, melatonin became the most frequently ingested substance among children reported to national poison control centers.”

Melatonin is a neurohormone that the body uses to regulate sleep. It's sold as a dietary supplement without a prescription. As the CDC states, in "2020, melatonin became the most frequently ingested substance among children reported to national poison control centers.”

Protecting Our Water Systems in the Age of Cyber Threats

By Susan Goldhaber MPH — May 23, 2023
When we turn on the tap, we all expect clean and safe drinking water. Threats to the cybersecurity of public drinking water systems are critical, but often overlooked, issues facing our country. The EPA is faced with the challenge of how to regulate these emerging threats. 

When we turn on the tap, we all expect clean and safe drinking water. Threats to the cybersecurity of public drinking water systems are critical, but often overlooked, issues facing our country. The EPA is faced with the challenge of how to regulate these emerging threats. 

Pharmacy Shelves are Bare of Many Critical Drugs, Frustrating Doctors and Endangering Patients. There's a Straightforward Policy Solution.

By Henry I. Miller, MS, MD — May 23, 2023
Drug shortages mean that many patients are getting the second or third choice of a medicine, increasing the likelihood that the drug will be ineffective or only suboptimally effective, or have unwanted side effects. Reciprocity of approvals between the U.S. and certain other countries could help to address that.

Drug shortages mean that many patients are getting the second or third choice of a medicine, increasing the likelihood that the drug will be ineffective or only suboptimally effective, or have unwanted side effects. Reciprocity of approvals between the U.S. and certain other countries could help to address that.

Which Came First, the Cannabis or the Schizophrenia?

By Chuck Dinerstein, MD, MBA — May 22, 2023
Within the timeframe of the legalization of recreational cannabis, there's been a rise in cannabis “use disorder” and the diagnosis of schizophrenia. It's become a chicken or egg which-came-first problem. A new study suggests cannabis is the gateway, creating 15% of new cases of schizophrenia annually.

Within the timeframe of the legalization of recreational cannabis, there's been a rise in cannabis “use disorder” and the diagnosis of schizophrenia. It's become a chicken or egg which-came-first problem. A new study suggests cannabis is the gateway, creating 15% of new cases of schizophrenia annually.

Pancreatic Cancer Cells Deprived of Glucose Find Another Fuel. A New Approach?

By Josh Bloom — May 22, 2023
A new study in the journal Nature examines what happens when pancreatic cancer cells are deprived of glucose, their normal fuel. Do the cells stop growing? No, they adapt by switching "fuels" to a different, ubiquitous biomolecule: uridine. The authors suggest that this discovery could lead to new treatments for this deadly cancer.

A new study in the journal Nature examines what happens when pancreatic cancer cells are deprived of glucose, their normal fuel. Do the cells stop growing? No, they adapt by switching "fuels" to a different, ubiquitous biomolecule: uridine. The authors suggest that this discovery could lead to new treatments for this deadly cancer.