Tetrahydrocanniboic Acid (THCA): Legal Until You Heat It, Maybe

By Josh Bloom — May 03, 2023
Our drug laws are almost supernaturally stupid. Part of this, aside from that they're largely made by morons, is the lack of knowledge of even basic chemistry, which could, at least, introduce a little sanity to the process. Here's a bit.

Our drug laws are almost supernaturally stupid. Part of this, aside from that they're largely made by morons, is the lack of knowledge of even basic chemistry, which could, at least, introduce a little sanity to the process. Here's a bit.

A Bee’s Tale

By Chuck Dinerstein, MD, MBA — May 03, 2023
Bumble bees are prolific pollinators, vital in creating the crops we eat. A new study shows how co-evolution between the bees and the plants can reduce the deaths of bumble bees.

Bumble bees are prolific pollinators, vital in creating the crops we eat. A new study shows how co-evolution between the bees and the plants can reduce the deaths of bumble bees.

Could Chemicals Have Caused Michael J. Fox's Parkinson's? It's Happened Before.

By Josh Bloom — May 02, 2023
Reflecting on the possible causes of his Parkinson's Disease, Fox recently told CBS News that he "did some damage" and that alcohol or chemical exposure could have contributed to – or even caused – his condition. While Fox’s comment is only speculation, a similar incident is not: in 1976, a young chemist inadvertently injected himself with a toxic impurity in a drug he made in his lab. It caused an unprecedented case of Parkinson's.

Reflecting on the possible causes of his Parkinson's Disease, Fox recently told CBS News that he "did some damage" and that alcohol or chemical exposure could have contributed to – or even caused – his condition. While Fox’s comment is only speculation, a similar incident is not: in 1976, a young chemist inadvertently injected himself with a toxic impurity in a drug he made in his lab. It caused an unprecedented case of Parkinson's.

ACSH Tries to Explain QALY

By Chuck Dinerstein, MD, MBA — May 02, 2023
Lost in the debate over how Medicare will negotiate drug prices, there's a concern by federal agencies about a metric used in determining a drug’s value. It's known as the Quality-Adjusted Life Year. There's bipartisan agreement in not using the term QALY, and “not even Medicare officials have signaled they want to use that approach.” What exactly are they talking about?

Lost in the debate over how Medicare will negotiate drug prices, there's a concern by federal agencies about a metric used in determining a drug’s value. It's known as the Quality-Adjusted Life Year. There's bipartisan agreement in not using the term QALY, and “not even Medicare officials have signaled they want to use that approach.” What exactly are they talking about?

COVID is Worse Than the Flu. Much Worse.

By Henry I. Miller, MS, MD — May 02, 2023
COVID is still killing more than 1,000 Americans a week; long COVID causes prolonged misery; and a new, more transmissible subvariant of the SARS-CoV-2 virus is spreading.

COVID is still killing more than 1,000 Americans a week; long COVID causes prolonged misery; and a new, more transmissible subvariant of the SARS-CoV-2 virus is spreading.

Is a Vegan Diet the Answer?

By Chuck Dinerstein, MD, MBA — May 01, 2023
As plant-based diets gain more traction, the vegan population, especially in high-income countries, is rising. Is veganism – avoiding products produced by, or from, animals – a healthy lifestyle? (Spoiler Alert: you already know the answer. Vegans, like the rest of us, have varying lifestyles, some of which are not as good as others.)

As plant-based diets gain more traction, the vegan population, especially in high-income countries, is rising. Is veganism – avoiding products produced by, or from, animals – a healthy lifestyle? (Spoiler Alert: you already know the answer. Vegans, like the rest of us, have varying lifestyles, some of which are not as good as others.)

Every Picture Tells a Story: COVID vs. the Flu

By Chuck Dinerstein, MD, MBA — Apr 28, 2023
Former President Trump said, “we have learned to live with it [COVID-19], just like we are learning to live with Covid, in most populations far less lethal!!!” before he recanted that statement with Bob Woodward, saying he knew it was "more deadly than even your strenuous flu." The morbidity and mortality of COVID have indeed changed over time; a recent study helps define whether COVID is becoming a new seasonal influenza.

Former President Trump said, “we have learned to live with it [COVID-19], just like we are learning to live with Covid, in most populations far less lethal!!!” before he recanted that statement with Bob Woodward, saying he knew it was "more deadly than even your strenuous flu." The morbidity and mortality of COVID have indeed changed over time; a recent study helps define whether COVID is becoming a new seasonal influenza.

Where Have All the Body Parts Gone?

The stakes are literally life and death. More than 100,000 patients are on the national transplant list, awaiting organ transplants, with thousands needlessly dying before receiving them. For now, a single nonprofit, The United Network for Organ Sharing (UNOS), is the sole organization responsible for matching organ recipients with donors. Last year the 42,888 organ transplants performed were just not enough.

The stakes are literally life and death. More than 100,000 patients are on the national transplant list, awaiting organ transplants, with thousands needlessly dying before receiving them. For now, a single nonprofit, The United Network for Organ Sharing (UNOS), is the sole organization responsible for matching organ recipients with donors. Last year the 42,888 organ transplants performed were just not enough.

What I'm Reading (Apr. 27)

By Chuck Dinerstein, MD, MBA — Apr 27, 2023
The mind-body problem is fake science Zombie pathogens have taken over my brain There is more to figs than the Newton Superstition, Enthusiasm, and Politics

The mind-body problem is fake science
Zombie pathogens have taken over my brain
There is more to figs than the Newton
Superstition, Enthusiasm, and Politics

Charles III Might Be King, but He’s Still the Dunce of Wales to Me

By Henry I. Miller, MS, MD — Apr 27, 2023
King Charles III's longstanding opposition to genetic engineering is misguided and unconstructive. Genetic modification has long made products better, safer, and cheaper.

King Charles III's longstanding opposition to genetic engineering is misguided and unconstructive. Genetic modification has long made products better, safer, and cheaper.