In 2016, the American viewing public was exposed to 663,000 television commercials for pharmaceuticals. That is a significant “ad spend” by Pharma, which we pay for through increased drug pricing. A new study looks at the therapeutic value of the more heavily advertised drugs. The key concept here is “market differentiation.”
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Medicine, like the science that underlies it, is seldom transformed by “Eureka” breakthroughs; rather, it is most often a process of systematically accumulating knowledge and making incremental advances. Radiation treatment for breast cancer is a good example: New data has enabled us to revise and improve old approaches.
Some doctors are alarmed by the blase attitude toward the Covid drug Paxlovid, quite different from when the drug first became available. What's going on? Some of the waning interest in the drug is because of the widespread use of the term "Paxlovid rebound," implying that there is something wrong with it. More likely, the problem is the term, not the drug.
Steal like an artist, Bob Dylan edition
India, Big Pharma to the World
Has tipping reached a tipping point?
Truffles or the magic of chemistry?
The 2016 and 2022 CDC opioid prescribing guidelines were based on the assertion that doctor over-prescribing to patients has been a major cause of opioid use disorder and overdose-related deaths. Published
data from the CDC and other sources reveals that this assertion was incorrect – and the CDC knew it was incorrect when it published its guidelines.
Making books
A Forest bath’s physiologic effects
Animals in the business zoo
Moynihan was right – It’s time to talk about absent fathers
Humans, trained to become radiologists, must pass a series of examinations to demonstrate their ability to accurately read and interpret images to be “board certified.” The training typically last five or more years; artificial intelligence has been training to take over the reading of these images for at least that long. This month, researchers asked an AI system to take radiology’s board exam; the results are not pretty.
China’s Zero-COVID policy goes against the central idea of the hygiene hypothesis: that to be the fittest to survive you must be exposed to germs. Could China’s current dilemma be sufficient proof of the need for a sweet spot between filth and sterility?
The question of the protection afforded by COVID infection vs. the immunity conferred by the mRNA vaccines is still unsettled. A new study may put our concerns to rest. Spoiler alert: each form of immunity has its strengths.
"Peer review" of scientific articles before publication is often considered the "gold standard" of reliability, but its luster has become tarnished by greed – the desire of the research community to tap into research funds, the pressure on scientists to publish or perish, and publishers of scientific journals seeking to maximize profits.
Let’s continue our countdown of the top articles written by ACSH this year.
Sweden has been the poster child of the live-free-or-die, no-lockdown crowd. The Great Barrington Declaration has its roots in the Swedish response. But beyond those snippets, what actually took place there? It is time for many of us, including myself, to find out.
How physicians communicate with their peers and their patients has come under more scrutiny of late. Patient access to “open” notes has raised concern about physicians using hurtful terms. A new paper considers the problem of physicians communicating with their patients unconsciously using jargon that obstructs rather than facilitates understanding.
Last year around Christmas, I wrote an article about mistletoe, a not-very-poisonous plant associated with the holiday. I am fascinated that so many plants related to the holiday have toxic elements. I’ve included a couple of highly poisonous plants, belladonna, and hemlock, that appear in some of the greatest literary works and my favorite mysteries.
Processed foods continue to get a bad rap
Geofencing January 6th Goes to Court
Zero COVID and Immune debt – Is China paying up?
And now, Dad Brain
Those who run the CDC and DEA have blood on their hands. No reasonable person can deny that the catastrophic crackdown on medical opioids has resulted in far more deaths than it saved. That’s because both patients and addicts are forced to turn to street drugs, and they end up dying from illicit fentanyl. But as ACSH Advisor Dr. Jeffrey Singer writes in Reason Magazine, there’s another harm that’s barely discussed: Suicides by those denied pain medications are becoming increasingly common.
Restaurants provide more than food and drink; they serve a social function, allowing friends to get together over a shared meal. Although as we age, ambient sound may make hearing one another increasingly difficult in this setting. Welcome to the Lombard Effect.
The Environmental Protection Agency (EPA) is in the process of making a remarkable decision and one that will have repercussions throughout the US. Its proposed safe levels in water for the “forever” chemicals perfluorooctanoate (PFOA) and its sulfonic acid (PFOS) are at extraordinary odds with other national authorities.
Medice, cura te ipsum. Physician, heal thyself. That is just what the CDC is beginning to do based on a recently published in-house structural review. Leave aside the shame and blame game of amnesty. What does the CDC believe it did wrong and could do better?
The Kaiser Family Foundation recently wrote a summary of what you actually get when you enroll in a Medicare Advantage (Part C) program.
A disease produces specific signs or symptoms. Symptoms are reported by patients and are largely subjective, while signs are elicited by physicians and have a more objective quality. Meanwhile, a syndrome is a set of symptoms suggesting the presence of an underlying disease or condition. And while COVID is a disease, long COVID remains an often-ill-defined syndrome.
If you watch TV, ads for Coca-Cola's Smart Water are inescapable. Also inescapable is that the ads suggest that the stuff will make you smart or perhaps offer some other health benefit. But the only thing smart about Smart Water is Coca-Cola's ability to make you shell out money to buy something you could pretty much get from a fire hydrant in Newark.
"It can disappear in a moment," Dr. Chuck Dinerstein said after his near-fatal battle with a pulmonary embolism. How should our mortality influence our worldviews? Unregulated medical devices may put patients in harm's way. Why is the Cleveland Clinic parroting anti-vaping talking points from the Truth Initiative?
It is widely accepted that animal testing is the gold standard in biological research. The facts debunk this belief. There are many reasons to object to animal testing, but the simple truth is that there is a better way.
Welcome to another edition of The J-Man Chronicles where we can guarantee that you'll never find anything the slightest bit useful, but quite possibly amusing and probably offensive. Today it's the Penis Drawing Plane and how not to get a leg extension.
Pagination
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