COVID, Steroids, and Do No Harm

By Chuck Dinerstein, MD, MBA — Apr 14, 2023
The Lancet reports that a clinical study of different doses of glucocorticoids for managing COVID pneumonia was stopped because treatment led to more deaths. There is power in saying, “We were wrong.”

The Lancet reports that a clinical study of different doses of glucocorticoids for managing COVID pneumonia was stopped because treatment led to more deaths. There is power in saying, “We were wrong.”

White House Declares Xylazine‐​Laced Fentanyl 'An Emerging Threat'

By Jeffrey Singer — Apr 13, 2023
First it was heroin. Next, it was fentanyl-laced heroin. Then it was fentanyl. Now it’s xylazine-laced fentanyl. Will nitazenes be next? Will policymakers ever learn that the Iron Law of Prohibition cannot be repealed?

First it was heroin. Next, it was fentanyl-laced heroin. Then it was fentanyl. Now it’s xylazine-laced fentanyl. Will nitazenes be next? Will policymakers ever learn that the Iron Law of Prohibition cannot be repealed?

Podcast: America's Troublesome Adderall Shortage; EPA's Nonsensical PFAS Water Standards

By Cameron English — Apr 13, 2023
A concerning shortage of Adderall, one of the drugs commonly used to treat attention deficit hyperactivity disorder (ADHD), is putting patients at risk. What caused it, and how can we fix it? The EPA has set new guidelines to keep PFAS out of drinking water. There's a problem, however: the agency's standards are absurd.

A concerning shortage of Adderall, one of the drugs commonly used to treat attention deficit hyperactivity disorder (ADHD), is putting patients at risk. What caused it, and how can we fix it? The EPA has set new guidelines to keep PFAS out of drinking water. There's a problem, however: the agency's standards are absurd.

Trans, DeTrans, & Lawsuits Determining the Standard of Care

Gender detransitioning – reversing your transition – is rare, in that less than one percent of persons choose to detransition. Related lawsuits are even rarer; so far, only two cases have been filed in the U.S. and a few in England. But the public reaction couldn’t be more different on both sides of the Atlantic.

Gender detransitioning – reversing your transition – is rare, in that less than one percent of persons choose to detransition. Related lawsuits are even rarer; so far, only two cases have been filed in the U.S. and a few in England. But the public reaction couldn’t be more different on both sides of the Atlantic.

The Conundrums of Prostate Cancer

By Henry I. Miller, MS, MD — Apr 13, 2023
Given the low mortality from slow-growing, localized prostate cancers and the side effects of many treatments, deciding whether to opt for monitoring or treatment can be excruciatingly difficult.

Given the low mortality from slow-growing, localized prostate cancers and the side effects of many treatments, deciding whether to opt for monitoring or treatment can be excruciatingly difficult.

Oregon Medical Board Should Resign – or Be Fired

By Red Lawhern — Apr 12, 2023
This body is trying to require all physicians to force-taper Oregon patients on prescribed opioids to less than 90 MME per day, or transition them to Buprenorphine. The Board should resign or be fired.

This body is trying to require all physicians to force-taper Oregon patients on prescribed opioids to less than 90 MME per day, or transition them to Buprenorphine. The Board should resign or be fired.

Does the Moon Make Us Mad?

By Chuck Dinerstein, MD, MBA — Apr 12, 2023
It's a commonly held belief that a full moon brings out the crazies and the craziness. The word "lunatic" – derived from the combination of "luna," or moon, and "atic," meaning “of the kind of” – was first mentioned in a fourth-century Bible. A new study looks at the influence of the moon and some circadian genes on the incidence of suicide. 

It's a commonly held belief that a full moon brings out the crazies and the craziness. The word "lunatic" – derived from the combination of "luna," or moon, and "atic," meaning “of the kind of” – was first mentioned in a fourth-century Bible. A new study looks at the influence of the moon and some circadian genes on the incidence of suicide. 

Untangling the Adderall Snafu

By Josh Bloom — Apr 12, 2023
Adderall, one of the primary drugs to treat ADHD, has been in the news lately because of a shortage. But there are a number of different ADHD drugs that contain amphetamine – the active ingredient in Adderall. Perhaps this will help clarify what's going on.

Adderall, one of the primary drugs to treat ADHD, has been in the news lately because of a shortage. But there are a number of different ADHD drugs that contain amphetamine – the active ingredient in Adderall. Perhaps this will help clarify what's going on.

Thinking Out Loud: From Bench to Bedside

By Chuck Dinerstein, MD, MBA — Apr 11, 2023
A not-so-recent paper estimated that for every £ spent on cardiovascular research, there was a continuing 9% savings in health costs 17 years later. If the time from the research bench to the bedside was reduced to 10 years, those continuing savings rose to 13%. Why does it take so long to translate medical science into medical care?

A not-so-recent paper estimated that for every £ spent on cardiovascular research, there was a continuing 9% savings in health costs 17 years later. If the time from the research bench to the bedside was reduced to 10 years, those continuing savings rose to 13%. Why does it take so long to translate medical science into medical care?