FDA’s Approval of New Alzheimer’s Drug is Real, But Very Modest, Advance

By Henry I. Miller, MS, MD — Jul 25, 2023
The drug, Leqembi, does not reverse symptoms. In patients in the early stages of Alzheimer's disease, it slowed cognitive and functional decline somewhat compared with placebo. The FDA’s approval of Leqembi is not the end of the Alzheimer’s journey, but it could be a way station. 

The drug, Leqembi, does not reverse symptoms. In patients in the early stages of Alzheimer's disease, it slowed cognitive and functional decline somewhat compared with placebo. The FDA’s approval of Leqembi is not the end of the Alzheimer’s journey, but it could be a way station. 

Every Picture Tells a Story: COVID Comes for Republicans

By Chuck Dinerstein, MD, MBA — Jul 24, 2023
A study confined to COVID deaths in Florida and Ohio suggests that the Grim Reaper’s “excess” deaths, when stratified by political party, came for Republicans more often than Democrats.

A study confined to COVID deaths in Florida and Ohio suggests that the Grim Reaper’s “excess” deaths, when stratified by political party, came for Republicans more often than Democrats.

Podcast: A.I.'s Growing (and Possibly) Harmful Impact on Medicine; Yes, Pop-Tarts Are Food

By Cameron English — Jul 24, 2023
Artificial Intelligence (AI) is playing an increasingly important role in health care. This could lower costs and streamline patient interactions—but the technology has a dark side, too. Critics of "ultra-processed" food often claim that certain snacks aren't even food. Let's debunk this myth, with a special focus on Pop-Tarts.

Artificial Intelligence (AI) is playing an increasingly important role in health care. This could lower costs and streamline patient interactions—but the technology has a dark side, too. Critics of "ultra-processed" food often claim that certain snacks aren't even food. Let's debunk this myth, with a special focus on Pop-Tarts.

US Continues to Push Failed Drug Policies: Drs. Singer and Bloom in The Daily Beast

By Josh Bloom — Jul 21, 2023
The harder the enforcement, the harder the drug – the iron law of prohibition – is alive and well in the U.S., unlike those who consume increasingly dangerous circulating drugs like xylazine (aka "tranq") and more powerful fentanyl analogs. Drs. Jeff Singer and Josh Bloom explain in an op-ed in The Daily Beast.

The harder the enforcement, the harder the drug – the iron law of prohibition – is alive and well in the U.S., unlike those who consume increasingly dangerous circulating drugs like xylazine (aka "tranq") and more powerful fentanyl analogs. Drs. Jeff Singer and Josh Bloom explain in an op-ed in The Daily Beast.

Thinking Out Loud: Artificial Intelligence Comes for Healthcare   

By Chuck Dinerstein, MD, MBA — Jul 21, 2023
While academics explore the bounty and pitfalls that Artificial Intelligence (AI) offers, and Big Tech continues to hype the possible over the actual, the feds seek to make regulations. Corporate healthcare, in all its forms, is fighting back. Should we be techno-optimists, Luddites, or somewhere in between?

While academics explore the bounty and pitfalls that Artificial Intelligence (AI) offers, and Big Tech continues to hype the possible over the actual, the feds seek to make regulations. Corporate healthcare, in all its forms, is fighting back. Should we be techno-optimists, Luddites, or somewhere in between?

Thebacon: An Opioid That You Can't Bring Home And Fry In A Pan

By Josh Bloom — Jul 21, 2023
There's a codeine analog with a strange name: "Thebacon." How does one pronounce this? Is it useful? And are there other obscure chemicals with meat-containing names? And A Dreaded Chemistry Lesson From Hell (TM) for no extra charge.

There's a codeine analog with a strange name: "Thebacon." How does one pronounce this? Is it useful? And are there other obscure chemicals with meat-containing names? And A Dreaded Chemistry Lesson From Hell (TM) for no extra charge.

What I'm Reading (July 19)

By Chuck Dinerstein, MD, MBA — Jul 20, 2023
Mosquito magnet Undercover journalism Daily Ice cream reduces heart disease How Madison Avenue taught us to consume healthcare

Mosquito magnet
Undercover journalism
Daily Ice cream reduces heart disease
How Madison Avenue taught us to consume healthcare

When You Can Read a Wrongdoer’s Mind

In criminal law, intent is necessary before guilt can be proven. Even civil actions, like intentional torts, pivot on intentionality.  Until now, intention was determined based on circumstantial evidence, with some jury guesswork. But what if it were possible to demonstrate someone’s state of mind objectively? What if there were no hiding behind a baby face or angry denial?

In criminal law, intent is necessary before guilt can be proven. Even civil actions, like intentional torts, pivot on intentionality.  Until now, intention was determined based on circumstantial evidence, with some jury guesswork. But what if it were possible to demonstrate someone’s state of mind objectively? What if there were no hiding behind a baby face or angry denial?

Harvard Drug Cocktail Will Make You Live Longer? Not So Fast

By Josh Bloom — Jul 20, 2023
A group of Harvard scientists claims that it has discovered cocktails of certain drugs that will help people live longer. Slow down fellas, you're not even close.

A group of Harvard scientists claims that it has discovered cocktails of certain drugs that will help people live longer. Slow down fellas, you're not even close.

Should You Get COVID and Flu Shots Together?

By Henry I. Miller, MS, MD — Jul 20, 2023
A clinical trial of various schedules for administering the two vaccines found that when they were administered together, "the quantitative and functional antibody responses were marginally lower compared to [COVID-19] booster vaccination alone. Lower protection against COVID-19 with concurrent administration of COVID-19 and influenza vaccination cannot be excluded." Thus, the data are somewhat equivocal, but I'll opt to get the two shots at different times.

A clinical trial of various schedules for administering the two vaccines found that when they were administered together, "the quantitative and functional antibody responses were marginally lower compared to [COVID-19] booster vaccination alone. Lower protection against COVID-19 with concurrent administration of COVID-19 and influenza vaccination cannot be excluded." Thus, the data are somewhat equivocal, but I'll opt to get the two shots at different times.